TIMM9

Across TCGA pan-cancer cohorts, TIMM9 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of TIMM9’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TIMM9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TIMM9 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, LIHC, and LUAD are the cancer types where TIMM9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TIMM9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.645	<.001	12	view →
LIHC	Male	II,III,IV	+1.282	<.001	9	view →
LUAD	Male	II,III,IV	+0.789	<.001	9	view →
KIRC	All	All	+0.342	<.001	9	view →
LUSC	Male	II,III,IV	+0.714	<.001	6	view →
COAD	All	II,III,IV	+0.689	<.001	6	view →
CHOL	Male	All	+1.818	<.001	5	view →
KIRP	All	II,III,IV	+0.457	.005	4	view →
READ	Male	All	+0.943	.005	3	view →
KICH	Female	All	−0.700	.002	3	view →
ESCA	All	All	+0.667	.002	2	view →
PRAD	All	All	+0.170	.034	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

TIMM9–HNSC

Open the HNSC breakdown →