TIMM8B

Across TCGA patient cohorts, TIMM8B protein abundance is significantly associated with the RNA expression of many other genes, with 11,521 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TIMM8B-associated genes across cancer lineages are EMP3, TIMM13, and TIMM8A. Each is linked with TIMM8B in more than 6 cancer types. Because this analysis shows association rather than direction, both TIMM8B-to-partner and partner-to-TIMM8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIMM8B versus EMP3 in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM8B→partner) and Y-score (partner→TIMM8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EMP3 →	-0.716	-0.610	<.001	<.001	3	7
LSCC	TIMM13 →	+0.665	+0.562	<.001	<.001	3	7
HNSC	TIMM8A →	+0.700	+0.498	<.001	<.001	3	6
LSCC	DSE →	-0.717	-0.670	<.001	<.001	3	5
COAD	GFPT2 →	-1.194	-0.561	<.001	<.001	3	5
OV	TMEM169 →	-0.946	-0.443	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,521 associations by consensus.

TIMM8B vs EMP3 — UCEC

Explore this scatter interactively →