TIMM8B

Across TCGA cell cohorts, TIMM8B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,230 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TIMM8B-associated GO terms across cancer lineages are Pyruvate decarboxylation to acetyl-CoA, Deadenylation-dependent decapping of nuclear-transcribed mRNA, and mRNA methylguanosine-cap decapping. Each is linked with TIMM8B in more than 15 cancer types. Because this analysis shows association rather than direction, both TIMM8B-to-partner and partner-to-TIMM8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyruvate decarboxylation to acetyl-CoA grouped by TIMM8B-low versus TIMM8B-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM8B→partner) and Y-score (partner→TIMM8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Pyruvate decarboxylation to acetyl-CoA →	+0.139	+0.715	<.001	<.001	3	16
URINARY_TRACT	Deadenylation-dependent decapping of nuclear-transcribed mRNA →	+0.109	+0.801	<.001	.001	3	14
URINARY_TRACT	mRNA methylguanosine-cap decapping →	+0.109	+0.950	<.001	.001	3	13
BONE	mRNA modification →	+0.096	+0.746	<.001	<.001	3	12
PANCREAS	Ether catabolic process →	+0.192	+0.789	.001	.002	3	12
PANCREAS	Glycerol ether catabolic process →	+0.192	+0.789	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,230 associations by consensus.

Pyruvate decarboxylation to acetyl-CoA by TIMM8B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →