TIMM50

Across TCGA cell cohorts, TIMM50 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,032 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TIMM50-associated GO terms across cancer lineages are DNA-templated transcription termination, Positive regulation of nuclear cell cycle DNA replication, and Metaphase/anaphase transition of mitotic cell cycle. Each is linked with TIMM50 in more than 17 cancer types. Because this analysis shows association rather than direction, both TIMM50-to-partner and partner-to-TIMM50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription termination grouped by TIMM50-low versus TIMM50-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM50→partner) and Y-score (partner→TIMM50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription termination →	+0.109	+0.900	.005	.006	3	18
BONE	Positive regulation of nuclear cell cycle DNA replication →	+0.162	+0.753	.005	.007	3	16
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.170	+0.673	<.001	<.001	3	16
BONE	rRNA transcription →	+0.118	+0.727	<.001	<.001	3	16
BONE	Metaphase/anaphase transition of cell cycle →	+0.175	+0.669	<.001	<.001	3	15
BONE	Transcription initiation at RNA polymerase I promoter →	+0.159	+1.112	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,032 associations by consensus.

DNA-templated transcription termination by TIMM50 expression — BONE

Explore this box plot interactively →