TIMM44

Across TCGA cell cohorts, TIMM44 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TIMM44-associated genes across cancer lineages are OR10W1, OR52H1, and MSH4. Each is linked with TIMM44 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIMM44-to-partner and partner-to-TIMM44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by TIMM44-low versus TIMM44-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM44→partner) and Y-score (partner→TIMM44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.009	+3.240	<.001	.004	3	1
LARGE_INTESTINE	OR52H1 →	+0.023	+3.084	<.001	.002	3	1
LARGE_INTESTINE	MSH4 →	+0.297	+3.464	<.001	.004	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10W1 by TIMM44 expression — LARGE_INTESTINE

Explore this box plot interactively →