TIMM17B

Across TCGA cell cohorts, TIMM17B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,003 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TIMM17B-associated GO terms across cancer lineages are Growth hormone secretion, Regulation of heterochromatin formation, and Nucleolus organization. Each is linked with TIMM17B in more than 12 cancer types. Because this analysis shows association rather than direction, both TIMM17B-to-partner and partner-to-TIMM17B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Growth hormone secretion grouped by TIMM17B-low versus TIMM17B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM17B→partner) and Y-score (partner→TIMM17B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Growth hormone secretion →	+0.145	+0.899	.001	.006	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of heterochromatin formation →	+0.106	+0.957	<.001	<.001	3	10
BONE	Nucleolus organization →	+0.100	+0.723	<.001	.002	3	9
BREAST	Cell-substrate adhesion →	-0.096	-0.758	.001	.002	3	9
BONE	Cell adhesion mediated by integrin →	-0.300	-1.042	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.104	+0.484	.001	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,003 associations by consensus.

Growth hormone secretion by TIMM17B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →