TIMM17A

Across TCGA patient cohorts, TIMM17A mutation is significantly associated with the RNA expression of many other genes, with 1,585 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TIMM17A-associated genes across cancer lineages are RNA5SP415, MIR519A1, and MIR8056. Each is linked with TIMM17A in more than 2 cancer types. Because this analysis shows association rather than direction, both TIMM17A-to-partner and partner-to-TIMM17A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP415 grouped by TIMM17A-low versus TIMM17A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM17A→partner) and Y-score (partner→TIMM17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP415 →	+0.466	+2.640	.003	.003	3	3
BLCA	MIR519A1 →	+0.439	+5.685	<.001	.003	3	2
BRCA	MIR8056 →	+0.352	+8.471	<.001	.005	3	1
BLCA	RNA5SP237 →	+0.402	+5.588	<.001	.004	3	1
BLCA	RNMTL1P2 →	+0.072	+6.814	<.001	<.001	3	1
BLCA	RNU7-74P →	+0.856	+7.307	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,585 associations by consensus.

RNA5SP415 by TIMM17A expression — UCEC

Explore this box plot interactively →