TIMM13

Across TCGA patient cohorts, TIMM13 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TIMM13-associated genes across cancer lineages are MIR5708, FCRL4, and RNU4-58P. Each is linked with TIMM13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIMM13-to-partner and partner-to-TIMM13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5708 grouped by TIMM13-low versus TIMM13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM13→partner) and Y-score (partner→TIMM13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5708 →	+0.275	+4.069	<.001	.008	3	1
UCEC	FCRL4 →	+0.241	+3.637	<.001	.002	3	1
UCEC	RNU4-58P →	+0.374	+3.811	<.001	<.001	3	1
UCEC	OR6K3 →	+0.164	+4.304	<.001	<.001	3	1
UCEC	RNU1-44P →	+0.377	+3.316	<.001	.002	3	1
UCEC	RNU6-1263P →	+0.477	+2.756	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

MIR5708 by TIMM13 expression — UCEC

Explore this box plot interactively →