TIMM10B

Across TCGA pan-cancer cohorts, TIMM10B Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TIMM10B data layer compared with 24 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher TIMM10B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TIMM10B expression acts as an unfavorable survival marker.

CESC and LIHC are the cancer types where TIMM10B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.053	0.823	<.001	42	view →
LIHC	DFS	Median	All	0.043	0.543	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TIMM10B–CESC (DFS)

Open the CESC breakdown →