TIMM10B

Across TCGA patient cohorts, TIMM10B mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TIMM10B-associated genes across cancer lineages are RNA5SP536, RN7SL468P, and RNA5SP273. Each is linked with TIMM10B in more than 1 cancer types. Because this analysis shows association rather than direction, both TIMM10B-to-partner and partner-to-TIMM10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP536 grouped by TIMM10B-low versus TIMM10B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM10B→partner) and Y-score (partner→TIMM10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP536 →	+0.697	+6.722	<.001	<.001	3	1
UCEC	RN7SL468P →	+0.349	+6.123	<.001	.002	3	1
UCEC	RNA5SP273 →	+2.212	+5.420	<.001	.005	3	1
UCEC	RNA5SP361 →	+0.724	+6.877	<.001	<.001	3	1
UCEC	RNA5SP405 →	+1.053	+6.582	<.001	.001	3	1
UCEC	RNU6-1284P →	+0.752	+5.186	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

RNA5SP536 by TIMM10B expression — UCEC

Explore this box plot interactively →