TIMM10B

Across TCGA cell cohorts, TIMM10B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,304 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TIMM10B-associated GO terms across cancer lineages are Telomere tethering at nuclear periphery, Telomere localization, and Spliceosomal tri-snRNP complex assembly. Each is linked with TIMM10B in more than 11 cancer types. Because this analysis shows association rather than direction, both TIMM10B-to-partner and partner-to-TIMM10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere tethering at nuclear periphery grouped by TIMM10B-low versus TIMM10B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM10B→partner) and Y-score (partner→TIMM10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Telomere tethering at nuclear periphery →	+0.169	+0.653	<.001	.001	3	12
SOFT_TISSUE	Telomere localization →	+0.167	+0.737	<.001	<.001	3	10
URINARY_TRACT	Spliceosomal tri-snRNP complex assembly →	+0.079	+0.685	.002	.004	3	10
BONE	Protein insertion into mitochondrial inner membrane →	+0.123	+0.705	<.001	.004	3	10
SOFT_TISSUE	Epidermis development →	-0.073	-0.513	.001	.001	3	9
URINARY_TRACT	Post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.114	+0.728	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,304 associations by consensus.

Telomere tethering at nuclear periphery by TIMM10B expression — SOFT_TISSUE

Explore this box plot interactively →