TIMM10

Across TCGA pan-cancer cohorts, TIMM10 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TIMM10 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TIMM10 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TIMM10 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

PDAC, GBM, and CCRCC are the cancer types where TIMM10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.951	0.709	.022	11	view →
GBM	OS	Median	All	0.658	0.418	.006	9	view →
CCRCC	DFS	Quartile	All	0.718	1.000	.007	8	view →
LUAD	OS	Median	II,III,IV	0.899	0.446	.018	7	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TIMM10–PDAC (OS)

Open the PDAC breakdown →