TIGD4

Across TCGA patient cohorts, TIGD4 protein abundance is significantly associated with the RNA expression of many other genes, with 131 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TIGD4-associated genes across cancer lineages are SPAG1, TENT5A, and TANC1. Each is linked with TIGD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIGD4-to-partner and partner-to-TIGD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIGD4 versus SPAG1 in LSCC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIGD4→partner) and Y-score (partner→TIGD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPAG1 →	+0.996	+0.646	.001	<.001	3	1
LSCC	TENT5A →	+0.939	+0.514	.006	.005	3	1
LSCC	TANC1 →	-0.747	-0.677	.004	.004	3	1
LSCC	RMDN3 →	-0.352	-0.570	.005	<.001	3	1
LSCC	MAT1A →	+0.746	+0.527	.002	.002	3	1
LSCC	LY6E →	+1.116	+0.570	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 131 associations by consensus.

TIGD4 vs SPAG1 — LSCC

Explore this scatter interactively →