TIGD4

Across TCGA cell cohorts, TIGD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,621 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TIGD4-associated GO terms across cancer lineages are Spliceosomal complex assembly, Mitochondrial electron transport, cytochrome c to oxygen, and Protein localization to cilium. Each is linked with TIGD4 in more than 10 cancer types. Because this analysis shows association rather than direction, both TIGD4-to-partner and partner-to-TIGD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal complex assembly grouped by TIGD4-low versus TIGD4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIGD4→partner) and Y-score (partner→TIGD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Spliceosomal complex assembly →	+0.083	+0.301	.002	.005	3	10
OVARY	Mitochondrial electron transport, cytochrome c to oxygen →	+0.069	+0.302	.006	<.001	3	10
BREAST	Protein localization to cilium →	+0.048	+0.333	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.108	+0.244	<.001	.001	3	10
SKIN	Cytoskeleton-dependent intracellular transport →	+0.039	+0.397	<.001	.002	2	11
PANCREAS	Translational initiation →	+0.075	+0.366	.002	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,621 associations by consensus.

Spliceosomal complex assembly by TIGD4 expression — OVARY

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