Across TCGA cell cohorts, TIGD1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TIGD1-associated genes across cancer lineages are KRTAP5-11, OR2AP1, and OR2AK2. Each is linked with TIGD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIGD1-to-partner and partner-to-TIGD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIGD1→partner) and Y-score (partner→TIGD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	KRTAP5-11 →	+0.045	+5.321	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR2AP1 →	+0.009	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR2AK2 →	+0.017	+3.947	.009	.004	3	1
LUNG_NSCLC_LUAD	GPR33 →	+0.014	+4.189	<.001	.002	3	1
LUNG_NSCLC_LUAD	C7orf77 →	+0.037	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

TIGD1 survival (RNA) · tumor vs normal (RNA) · all TIGD1 data types