TIFAB

Across TCGA patient cohorts, TIFAB protein abundance is significantly associated with the RNA expression of many other genes, with 600 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TIFAB-associated genes across cancer lineages are PPIL2, SLC25A14, and HTATSF1. Each is linked with TIFAB in more than 1 cancer types. Because this analysis shows association rather than direction, both TIFAB-to-partner and partner-to-TIFAB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIFAB versus PPIL2 in LSCC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIFAB→partner) and Y-score (partner→TIFAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPIL2 →	-0.496	-0.417	.005	.004	3	1
LSCC	SLC25A14 →	-0.542	-0.398	<.001	.003	3	1
LSCC	HTATSF1 →	-0.663	-0.568	<.001	<.001	3	1
LSCC	GLA →	-0.719	-0.515	<.001	<.001	3	1
LSCC	NECAB2 →	-1.727	-0.481	.005	.008	3	1
LSCC	SPAG1 →	+0.646	+0.469	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 600 associations by consensus.

TIFAB vs PPIL2 — LSCC

Explore this scatter interactively →