TIFAB

Across TCGA cell cohorts, TIFAB RNA expression is significantly associated with the go_rna of many other GO terms, with 728 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TIFAB-associated GO terms across cancer lineages are Negative regulation of saliva secretion, Hard palate morphogenesis, and Mastication. Each is linked with TIFAB in more than 3 cancer types. Because this analysis shows association rather than direction, both TIFAB-to-partner and partner-to-TIFAB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of saliva secretion grouped by TIFAB-low versus TIFAB-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIFAB→partner) and Y-score (partner→TIFAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of saliva secretion →	+0.762	+1.253	<.001	<.001	3	4
BLOOD_Leukemia	Hard palate morphogenesis →	+0.762	+1.253	<.001	<.001	3	4
BLOOD_Leukemia	Mastication →	+0.762	+1.253	<.001	<.001	3	4
BLOOD_Leukemia	Learned vocalization behavior →	+0.762	+1.253	<.001	<.001	3	4
BLOOD_Leukemia	Regulation of dopaminergic neuron differentiation →	-0.402	-0.775	<.001	.007	3	3
LUNG_NSCLC_LUAD	Regulation of calcium ion export across plasma membrane →	+0.062	+0.001	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 728 associations by consensus.

Negative regulation of saliva secretion by TIFAB expression — BLOOD_Leukemia

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