TIFA

Across TCGA patient cohorts, TIFA RNA expression is significantly associated with the protein abundance of many other proteins, with 11,579 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TIFA-associated proteins across cancer lineages are SPTBN1_T999, STRN3, and HPF1. Each is linked with TIFA in more than 3 cancer types. Because this analysis shows association rather than direction, both TIFA-to-partner and partner-to-TIFA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIFA versus SPTBN1_T999 in UCEC, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TIFA→partner) and Y-score (partner→TIFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPTBN1_T999 →	-0.536	-0.582	.005	.004	3	4
HNSC	STRN3 →	-0.414	-0.639	<.001	<.001	3	4
OV	HPF1 →	+0.313	+0.588	<.001	.003	3	4
GBM	FMNL1 →	+0.502	+0.568	<.001	<.001	3	4
PDAC	ARG1 →	+0.806	+0.365	<.001	<.001	3	4
COAD	OTUD4 →	+0.313	+0.643	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,579 associations by consensus.

TIFA vs SPTBN1_T999 — UCEC

Explore this scatter interactively →