TICRR

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TICRR protein abundance is significantly associated with the RNA expression of many other genes, with 3,242 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TICRR-associated genes across cancer lineages are FZD7, SLC29A4, and SNHG21. Each is linked with TICRR in more than 1 cancer types. Because this analysis shows association rather than direction, both TICRR-to-partner and partner-to-TICRR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TICRR versus FZD7 in LSCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TICRR→partner) and Y-score (partner→TICRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCFZD7 →+2.241+1.224<.001<.00132
LSCCSLC29A4 →+1.235+0.999.006<.00132
LSCCSNHG21 →+0.748+1.160.001.00132
HNSCC2CD5 →+0.999+0.870.009.00132
HNSCFANCL →+1.062+0.746.002.00232
HNSCFLRT3 →-1.589-0.591<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,242 associations by consensus.

TICRR vs FZD7 — LSCC

Per-sample scatter of TICRR vs FZD7 in LSCC (Pearson r = 0.56).

Explore this scatter interactively →

Exploration