TICRR

Across TCGA cell cohorts, TICRR RNA expression is significantly associated with the go_rna of many other GO terms, with 5,388 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TICRR-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Negative regulation of cell cycle phase transition, and Negative regulation of cell cycle G2/M phase transition. Each is linked with TICRR in more than 19 cancer types. Because this analysis shows association rather than direction, both TICRR-to-partner and partner-to-TICRR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by TICRR-low versus TICRR-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TICRR→partner) and Y-score (partner→TICRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle process →	+0.076	+1.193	<.001	<.001	3	20
OESOPHAGUS	Negative regulation of cell cycle phase transition →	+0.081	+1.189	<.001	.001	3	20
BONE	Negative regulation of cell cycle G2/M phase transition →	+0.110	+1.897	<.001	.001	3	20
BLOOD_Myeloma	Mitotic DNA replication →	+0.185	+1.222	<.001	.004	3	20
OESOPHAGUS	Nuclear division →	+0.084	+0.878	<.001	.002	3	20
BREAST	Chromosome condensation →	+0.184	+1.192	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,388 associations by consensus.

Negative regulation of cell cycle process by TICRR expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →