THUMPD3

Across TCGA cell cohorts, THUMPD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,543 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible THUMPD3-associated GO terms across cancer lineages are DNA-templated DNA replication, Mitotic spindle assembly, and Regulation of double-strand break repair. Each is linked with THUMPD3 in more than 13 cancer types. Because this analysis shows association rather than direction, both THUMPD3-to-partner and partner-to-THUMPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by THUMPD3-low versus THUMPD3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THUMPD3→partner) and Y-score (partner→THUMPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA-templated DNA replication →	+0.083	+0.579	<.001	<.001	3	14
BLOOD_Myeloma	Mitotic spindle assembly →	+0.116	+1.001	<.001	<.001	3	12
SOFT_TISSUE	Regulation of double-strand break repair →	+0.075	+0.610	.001	<.001	2	13
SOFT_TISSUE	Regulation of mitotic metaphase/anaphase transition →	+0.143	+0.729	<.001	<.001	3	12
BLOOD_Myeloma	Spindle assembly →	+0.089	+0.562	<.001	<.001	3	12
BLOOD_Lymphoma	DNA replication →	+0.075	+0.652	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,543 associations by consensus.

DNA-templated DNA replication by THUMPD3 expression — SOFT_TISSUE

Explore this box plot interactively →