THUMPD2

Across TCGA patient cohorts, THUMPD2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,534 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible THUMPD2-associated genes across cancer lineages are CSGALNACT2P1, BSN, and DNAJC2. Each is linked with THUMPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both THUMPD2-to-partner and partner-to-THUMPD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THUMPD2 versus CSGALNACT2P1 in HNSC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THUMPD2→partner) and Y-score (partner→THUMPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CSGALNACT2P1 →	+1.168	+0.912	.001	<.001	3	2
LSCC	BSN →	+0.351	+0.397	.005	.001	3	2
LSCC	DNAJC2 →	+0.465	+0.302	.002	.002	3	2
LSCC	GLRX3 →	+0.478	+0.400	.004	.001	3	2
LSCC	CENPA →	+0.652	+0.311	.001	<.001	3	2
BRCA	PRR7 →	+0.820	+0.255	.005	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,534 associations by consensus.

THUMPD2 vs CSGALNACT2P1 — HNSC

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