THUMPD2

Across TCGA cell cohorts, THUMPD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,982 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible THUMPD2-associated GO terms across cancer lineages are RNA methylation, tRNA modification, and Mitotic DNA damage checkpoint signaling. Each is linked with THUMPD2 in more than 11 cancer types. Because this analysis shows association rather than direction, both THUMPD2-to-partner and partner-to-THUMPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA methylation grouped by THUMPD2-low versus THUMPD2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THUMPD2→partner) and Y-score (partner→THUMPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RNA methylation →	+0.055	+0.523	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	tRNA modification →	+0.042	+0.873	.006	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitotic DNA damage checkpoint signaling →	+0.088	+0.926	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.072	+0.692	<.001	<.001	3	12
SOFT_TISSUE	Nuclear pore complex assembly →	+0.128	+0.624	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.063	+0.917	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,982 associations by consensus.

RNA methylation by THUMPD2 expression — SKIN

Explore this box plot interactively →