Across TCGA pan-cancer cohorts, THUMPD1P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of THUMPD1P1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where THUMPD1P1 RNA is repressed in tumor relative to normal tissue. In most cancer types THUMPD1P1 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA and LUAD are the cancer types where THUMPD1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in THUMPD1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.015	.011	4	view →
LUAD	All	II,III,IV	+0.012	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: THUMPD1P1 RNA expression & survival · all THUMPD1P1 data types