Q-omics provides the consensus-scored THUMPD1P1 profile across patient tissues and cancer cell-line models. THUMPD1P1 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, THUMPD1P1 is differentially expressed in 2, with the highest sampling consensus in BRCA. Additionally, THUMPD1P1 RNA expression shows 6,201 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KICH, BRCA, and STAD as cancer lineages where THUMPD1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for THUMPD1P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes THUMPD1P1 survival associations across molecular data types. THUMPD1P1 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible THUMPD1P1 RNA expression–survival associations across cancer types. High THUMPD1P1 expression shows unfavorable associations in KICH, ACC, CESC, LUSC and KIRC, but favorable associations in BRCA. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for THUMPD1P1 RNA expression.
This table summarizes THUMPD1P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for THUMPD1P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. THUMPD1P1 shows lower tumor expression in BRCA and higher tumor expression in LUAD. The BRCA box plot shows higher THUMPD1P1 RNA expression in normal versus tumor tissue (log2 FC = −0.015, t-test p = .011).
This table shows molecular features associated with THUMPD1P1 in patient tissues and cancer cell lines. In patient samples, THUMPD1P1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
