THTPA

Across TCGA cell cohorts, THTPA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,165 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible THTPA-associated GO terms across cancer lineages are Thiamine metabolic process, Regulation of intracellular estrogen receptor signaling pathway, and Water-soluble vitamin biosynthetic process. Each is linked with THTPA in more than 16 cancer types. Because this analysis shows association rather than direction, both THTPA-to-partner and partner-to-THTPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Thiamine metabolic process grouped by THTPA-low versus THTPA-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THTPA→partner) and Y-score (partner→THTPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Thiamine metabolic process →	+1.212	+0.706	<.001	<.001	3	17
KIDNEY	Regulation of intracellular estrogen receptor signaling pathway →	+0.093	+0.868	.001	.001	3	14
PANCREAS	Water-soluble vitamin biosynthetic process →	+0.129	+0.925	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Cytoskeleton-dependent intracellular transport →	+0.065	+0.821	<.001	.009	3	12
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.087	+0.689	.009	.002	3	12
LUNG_NSCLC_LUSC	Transport along microtubule →	+0.047	+0.844	.005	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,165 associations by consensus.

Thiamine metabolic process by THTPA expression — LIVER

Explore this box plot interactively →