THSD7B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, THSD7B protein abundance is significantly associated with the RNA expression of many other genes, with 813 significant associations in total. COAD shows the largest number of these associations.

The most reproducible THSD7B-associated genes across cancer lineages are ETV7, TXN2, and POFUT1. Each is linked with THSD7B in more than 1 cancer types. Because this analysis shows association rather than direction, both THSD7B-to-partner and partner-to-THSD7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THSD7B versus ETV7 in COAD, with a Pearson correlation of -0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THSD7B→partner) and Y-score (partner→THSD7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADETV7 →-2.126-0.969.005.00231
COADTXN2 →-0.970-0.969.002.00231
COADPOFUT1 →+0.703+0.969.003.00231
COADRP2 →-0.573-0.969.007.00231
COADMAZ →-0.816-0.969.005.00231
COADCSK →-1.116-0.969.004.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 813 associations by consensus.

THSD7B vs ETV7 — COAD

Per-sample scatter of THSD7B vs ETV7 in COAD (Pearson r = -0.87).

Explore this scatter interactively →

Exploration