THSD7B

Across TCGA cell cohorts, THSD7B RNA expression is significantly associated with the go_rna of many other GO terms, with 975 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible THSD7B-associated GO terms across cancer lineages are Protein-RNA complex organization, RNA decapping, and Spliceosomal snRNP assembly. Each is linked with THSD7B in more than 7 cancer types. Because this analysis shows association rather than direction, both THSD7B-to-partner and partner-to-THSD7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-RNA complex organization grouped by THSD7B-low versus THSD7B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THSD7B→partner) and Y-score (partner→THSD7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein-RNA complex organization →	+0.061	+1.987	.002	.005	3	8
KIDNEY	RNA decapping →	+0.045	+0.035	.002	.004	2	7
BLOOD_Leukemia	Spliceosomal snRNP assembly →	+0.039	+0.239	<.001	.009	3	6
OVARY	Protein-RNA complex assembly →	+0.041	+0.378	.001	.008	2	7
STOMACH	Nuclear-transcribed mRNA catabolic process →	+0.056	+0.139	<.001	.005	2	6
STOMACH	Monoatomic anion transmembrane transport →	-0.055	-0.205	.003	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 975 associations by consensus.

Protein-RNA complex organization by THSD7B expression — LUNG_SCLC

Explore this box plot interactively →