THSD1

Across TCGA cell cohorts, THSD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,248 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible THSD1-associated GO terms across cancer lineages are Chaperone-mediated autophagy, Cellular response to copper ion, and Positive regulation of focal adhesion assembly. Each is linked with THSD1 in more than 9 cancer types. Because this analysis shows association rather than direction, both THSD1-to-partner and partner-to-THSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chaperone-mediated autophagy grouped by THSD1-low versus THSD1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THSD1→partner) and Y-score (partner→THSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Chaperone-mediated autophagy →	+0.180	+0.998	<.001	.001	2	10
LUNG_NSCLC_LUSC	Cellular response to copper ion →	+0.235	+1.529	<.001	<.001	3	9
BONE	Positive regulation of focal adhesion assembly →	+0.156	+1.194	.003	.003	3	9
LUNG_NSCLC_LUAD	Regulation of extracellular matrix organization →	+0.072	+0.743	<.001	.002	3	9
STOMACH	Receptor-mediated endocytosis of virus by host cell →	+0.210	+1.050	<.001	<.001	3	9
OESOPHAGUS	Positive regulation of tumor necrosis factor superfamily cytokine production →	+0.080	+1.198	.003	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,248 associations by consensus.

Chaperone-mediated autophagy by THSD1 expression — PANCREAS

Explore this box plot interactively →