THRA

Across TCGA cell cohorts, THRA RNA expression is significantly associated with the RNA expression of many other genes, with 9,763 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible THRA-associated genes across cancer lineages are MSL1, RARA, and MED24. Each is linked with THRA in more than 12 cancer types. Because this analysis shows association rather than direction, both THRA-to-partner and partner-to-THRA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THRA versus MSL1 in BREAST, with a Pearson correlation of 0.55.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THRA→partner) and Y-score (partner→THRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MSL1 →	+1.788	+1.585	<.001	<.001	3	13
BREAST	RARA →	+1.485	+1.113	<.001	<.001	3	12
BREAST	MED24 →	+1.143	+1.071	<.001	<.001	3	11
LIVER	NOL4L →	+2.295	+1.813	<.001	<.001	3	11
LUNG_NSCLC_LUSC	PIP4K2B →	+1.105	+1.477	<.001	<.001	2	12
UPPER_AERODIGESTIVE_TRACT	FLYWCH2 →	+0.931	+1.326	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,763 associations by consensus.

THRA vs MSL1 — BREAST

Explore this scatter interactively →