THOC7

Across TCGA patient cohorts, THOC7 protein abundance is significantly associated with the RNA expression of many other genes, with 15,866 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible THOC7-associated genes across cancer lineages are THOC2, THOC1, and METTL4. Each is linked with THOC7 in more than 6 cancer types. Because this analysis shows association rather than direction, both THOC7-to-partner and partner-to-THOC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THOC7 versus THOC2 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THOC7→partner) and Y-score (partner→THOC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	THOC2 →	+0.548	+0.196	<.001	<.001	3	7
LSCC	THOC1 →	+0.680	+0.282	<.001	<.001	3	7
HNSC	METTL4 →	+0.648	+0.177	.001	<.001	3	6
LSCC	CEP76 →	+0.806	+0.313	<.001	<.001	3	6
UCEC	FBL →	+1.053	+0.222	<.001	<.001	3	6
LSCC	TIMM8A →	+0.736	+0.272	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,866 associations by consensus.

THOC7 vs THOC2 — HNSC

Explore this scatter interactively →