THOC7

Across TCGA pan-cancer cohorts, THOC7 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated THOC7 data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher THOC7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated THOC7 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUSC show a favorable association.

LIHC, KICH, and ACC are the cancer types where THOC7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.459	0.621	<.001	104	view →
KICH	DFS	Tertile	II,III,IV	0.424	0.944	.001	78	view →
ACC	DFS	Median	All	0.268	0.634	<.001	75	view →
SCLC	OS	Median	All	0.431	0.692	.001	58	view →
LGG	OS	Tertile	All	0.721	0.874	<.001	33	view →
PAAD	OS	Median	All	0.308	0.480	.015	25	view →
UCEC	DFS	Median	IV	0.255	0.737	<.001	24	view →
COAD	OS	Quartile	II,III,IV	0.849	0.697	.010	20	view →
ESCA	DFS	Quartile	All	0.480	0.705	.018	19	view →
LUSC	OS	Tertile	All	0.855	0.729	.005	18	view →
GBM	OS	Median	All	0.344	0.474	.004	15	view →
UVM	OS	Median	III,IV	0.302	1.000	.008	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

THOC7–LIHC (DFS)

Open the LIHC breakdown →