THOC7

Across TCGA patient cohorts, THOC7 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible THOC7-associated genes across cancer lineages are MIR6803, RNA5SP414, and RNVU1-19. Each is linked with THOC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both THOC7-to-partner and partner-to-THOC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by THOC7-low versus THOC7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THOC7→partner) and Y-score (partner→THOC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.307	+5.671	<.001	<.001	3	2
UCEC	RNA5SP414 →	+0.555	+2.933	.005	.006	3	1
UCEC	RNVU1-19 →	+0.819	+2.955	<.001	.007	3	1
UCEC	RNA5SP411 →	+1.870	+2.715	<.001	.006	3	1
UCEC	MIR8080 →	+0.305	+4.335	<.001	<.001	3	1
UCEC	RNA5SP412 →	+0.956	+3.967	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

MIR6803 by THOC7 expression — UCEC

Explore this box plot interactively →