THOC7

Across TCGA cell cohorts, THOC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,917 significant associations in total. BONE shows the largest number of these associations.

The most reproducible THOC7-associated GO terms across cancer lineages are Purine deoxyribonucleoside monophosphate biosynthetic process, DAMP biosynthetic process, and tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation. Each is linked with THOC7 in more than 12 cancer types. Because this analysis shows association rather than direction, both THOC7-to-partner and partner-to-THOC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine deoxyribonucleoside monophosphate biosynthetic process grouped by THOC7-low versus THOC7-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THOC7→partner) and Y-score (partner→THOC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.108	+0.715	.001	<.001	3	13
KIDNEY	DAMP biosynthetic process →	+0.108	+0.715	.001	<.001	3	13
URINARY_TRACT	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.128	+0.744	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome, centromeric region →	+0.144	+0.693	.001	.009	2	11
OESOPHAGUS	Cerebral cortex radial glia-guided migration →	-0.171	-0.997	<.001	<.001	3	10
OESOPHAGUS	Telencephalon glial cell migration →	-0.171	-0.997	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,917 associations by consensus.

Purine deoxyribonucleoside monophosphate biosynthetic process by THOC7 expression — KIDNEY

Explore this box plot interactively →