THOC7-AS1

Across TCGA pan-cancer cohorts, THOC7-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated THOC7-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher THOC7-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated THOC7-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and UCEC show a favorable association.

KICH, OV, and UCEC are the cancer types where THOC7-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	III,IV	0.217	0.869	<.001	92	view →
OV	DFS	Median	All	0.201	0.121	.002	48	view →
UCEC	DFS	Tertile	IV	0.904	0.283	<.001	36	view →
ACC	OS	Tertile	III,IV	0.197	0.660	.022	28	view →
READ	OS	Median	All	0.940	0.299	.001	19	view →
PAAD	DFS	Quartile	II,III,IV	0.315	0.487	.017	15	view →
LUAD	DFS	Tertile	All	0.617	0.356	.008	14	view →
HNSC	OS	Tertile	II,III,IV	0.509	0.321	.022	10	view →
BRCA	DFS	Median	III,IV	0.920	0.840	.013	9	view →
CHOL	OS	Quartile	III,IV	0.136	0.839	.008	9	view →
THCA	OS	Median	All	0.982	0.918	.017	9	view →
SARC	DFS	Tertile	All	0.454	0.648	.014	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

THOC7-AS1–KICH (DFS)

Open the KICH breakdown →