THOC7-AS1

Across TCGA pan-cancer cohorts, THOC7-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of THOC7-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where THOC7-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types THOC7-AS1 is over-expressed in tumor, although a few such as LUAD and STAD show the opposite, repressed pattern.

COAD, LIHC, and LUAD are the cancer types where THOC7-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in THOC7-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.184	.002	4	view →
LIHC	All	All	+0.030	.002	3	view →
LUAD	Female	III,IV	−0.236	.019	2	view →
PRAD	All	All	+0.194	<.001	2	view →
STAD	Male	III,IV	−0.311	.020	1	view →
CHOL	Male	All	+0.146	.004	1	view →
THCA	All	II,III,IV	−0.092	.025	1	view →
KIRC	Male	III,IV	−0.054	.021	1	view →
HNSC	Female	All	+0.047	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

THOC7-AS1–COAD

Open the COAD breakdown →