THOC3

Across TCGA pan-cancer cohorts, THOC3 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated THOC3 data layer compared with 22 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher THOC3 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated THOC3 expression acts as an unfavorable survival marker.

READ are the cancer types where THOC3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Median	II,III,IV	0.082	0.800	<.001	21	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

THOC3–READ (DFS)

Open the READ breakdown →