THOC3

Across TCGA patient cohorts, THOC3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,796 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible THOC3-associated genes across cancer lineages are ZFP62, GMPS, and EXO1. Each is linked with THOC3 in more than 7 cancer types. Because this analysis shows association rather than direction, both THOC3-to-partner and partner-to-THOC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THOC3 versus ZFP62 in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THOC3→partner) and Y-score (partner→THOC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZFP62 →	+0.651	+0.280	<.001	<.001	3	8
LSCC	GMPS →	+0.946	+0.407	<.001	<.001	3	6
GBM	EXO1 →	+1.137	+0.280	<.001	<.001	3	6
OV	RACK1 →	+0.940	+0.387	<.001	<.001	3	6
LUAD	TCOF1 →	+0.483	+0.277	<.001	<.001	3	6
LSCC	DDX55 →	+0.483	+0.355	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,796 associations by consensus.

THOC3 vs ZFP62 — OV

Explore this scatter interactively →