THNSL2

Across TCGA pan-cancer cohorts, THNSL2 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated THNSL2 data layer compared with 19 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher THNSL2 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated THNSL2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, PRAD, and HNSC are the cancer types where THNSL2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	1.000	0.434	.008	26	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
HNSC	OS	Median	All	0.166	0.710	.003	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

THNSL2–UCEC (DFS)

Open the UCEC breakdown →