THNSL2

Across TCGA patient cohorts, THNSL2 mutation is significantly associated with the RNA expression of many other genes, with 1,907 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible THNSL2-associated genes across cancer lineages are MIR193BHG, PTS, and GPR180. Each is linked with THNSL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both THNSL2-to-partner and partner-to-THNSL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR193BHG grouped by THNSL2-low versus THNSL2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THNSL2→partner) and Y-score (partner→THNSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR193BHG →	+0.610	+2.917	<.001	<.001	3	3
UCEC	PTS →	+0.370	+2.923	.001	<.001	3	2
UCEC	GPR180 →	+0.421	+2.246	.003	.005	3	2
UCEC	MED27 →	+0.392	+2.523	<.001	<.001	3	2
UCEC	PEX13 →	+0.419	+2.502	.003	.001	3	2
UCEC	ZMYND19 →	+0.528	+3.617	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,907 associations by consensus.

MIR193BHG by THNSL2 expression — UCEC

Explore this box plot interactively →