Across TCGA patient cohorts, THNSL1 mutation is significantly associated with the RNA expression of many other genes, with 5,484 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible THNSL1-associated genes across cancer lineages are PTP4A3, ACYP1, and RNU6-718P. Each is linked with THNSL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both THNSL1-to-partner and partner-to-THNSL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THNSL1→partner) and Y-score (partner→THNSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PTP4A3 →	-0.866	-1.632	<.001	<.001	3	3
UCEC	ACYP1 →	+0.333	+3.234	.003	<.001	3	3
SKCM	RNU6-718P →	+0.660	+2.858	<.001	.007	3	2
SKCM	LINC01490 →	+0.025	+3.224	<.001	.007	3	2
KIRC	TUBB1P2 →	+0.039	+8.025	<.001	.007	3	2
UCEC	ADAM33 →	-0.765	-4.195	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,484 associations by consensus.

Exploration

THNSL1 survival (RNA) · tumor vs normal (RNA) · all THNSL1 data types