THBS1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, THBS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,843 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible THBS1-associated proteins across cancer lineages are ACTN1, AEBP1, and CLEC3B. Each is linked with THBS1 in more than 8 cancer types. Because this analysis shows association rather than direction, both THBS1-to-partner and partner-to-THBS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THBS1 versus ACTN1 in UCEC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THBS1→partner) and Y-score (partner→THBS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECACTN1 →+0.520+1.233<.001<.00139
OVAEBP1 →+0.799+1.659<.001<.00139
BRCACLEC3B →+0.675+1.181<.001<.00139
GBMCOL6A3 →+1.324+1.635<.001<.00139
OVFLNA →+0.637+1.892<.001<.00139
OVFLNA_S1630 →+0.799+1.104<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,843 associations by consensus.

THBS1 vs ACTN1 — UCEC

Per-sample scatter of THBS1 vs ACTN1 in UCEC (Pearson r = 0.57).

Explore this scatter interactively →

Exploration