THBD

Across TCGA patient cohorts, THBD protein abundance is significantly associated with the RNA expression of many other genes, with 12,398 significant associations in total. GBM shows the largest number of these associations.

The most reproducible THBD-associated genes across cancer lineages are GLCCI1, SERPINE1, and LOX. Each is linked with THBD in more than 3 cancer types. Because this analysis shows association rather than direction, both THBD-to-partner and partner-to-THBD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THBD versus GLCCI1 in HNSC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THBD→partner) and Y-score (partner→THBD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GLCCI1 →	-0.890	-0.776	<.001	<.001	3	4
GBM	SERPINE1 →	+1.469	+0.758	<.001	<.001	3	3
GBM	LOX →	+1.096	+0.756	<.001	<.001	3	3
PDAC	CSF3R →	+0.858	+0.409	<.001	.001	3	3
GBM	SPOCD1 →	+2.403	+1.036	<.001	<.001	3	3
OV	LRRC32 →	+1.063	+0.788	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,398 associations by consensus.

THBD vs GLCCI1 — HNSC

Explore this scatter interactively →