THBD

Across TCGA patient cohorts, THBD protein abundance is significantly associated with the protein abundance of many other proteins, with 19,424 significant associations in total. GBM shows the largest number of these associations.

The most reproducible THBD-associated proteins across cancer lineages are NELFA, SART1, and CAV1. Each is linked with THBD in more than 5 cancer types. Because this analysis shows association rather than direction, both THBD-to-partner and partner-to-THBD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THBD versus NELFA in HNSC, with a Pearson correlation of -0.42.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THBD→partner) and Y-score (partner→THBD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NELFA →	-0.287	-0.880	<.001	<.001	3	5
GBM	SART1 →	-0.223	-0.562	.005	.001	2	6
GBM	CAV1 →	+0.707	+0.562	<.001	<.001	3	5
GBM	TLR2 →	+0.520	+0.754	<.001	<.001	3	4
GBM	VCL_S434 →	+0.933	+0.863	<.001	<.001	3	4
PDAC	PIEZO1 →	+0.773	+0.502	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,424 associations by consensus.

THBD vs NELFA — HNSC

Explore this scatter interactively →