THAP8

Across TCGA patient cohorts, THAP8 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,509 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible THAP8-associated proteins across cancer lineages are TBCB, THOC6, and UBA2. Each is linked with THAP8 in more than 6 cancer types. Because this analysis shows association rather than direction, both THAP8-to-partner and partner-to-THAP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THAP8 versus TBCB in PDAC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP8→partner) and Y-score (partner→THAP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TBCB →	+0.329	+0.357	.001	<.001	3	7
GBM	THOC6 →	+0.259	+0.285	.002	.007	3	5
GBM	UBA2 →	+0.355	+0.350	<.001	.001	3	5
COAD	ZMYM3 →	+0.509	+0.397	<.001	.002	3	5
LSCC	SAE1 →	+0.326	+0.582	<.001	<.001	3	4
LSCC	SMARCA1 →	+0.416	+0.348	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,509 associations by consensus.

THAP8 vs TBCB — PDAC

Explore this scatter interactively →