THAP8

Across TCGA cell cohorts, THAP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,902 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible THAP8-associated GO terms across cancer lineages are Cytoskeleton-dependent cytokinesis, Cytokinesis, and Negative regulation of calcium ion export across plasma membrane. Each is linked with THAP8 in more than 14 cancer types. Because this analysis shows association rather than direction, both THAP8-to-partner and partner-to-THAP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent cytokinesis grouped by THAP8-low versus THAP8-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP8→partner) and Y-score (partner→THAP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cytoskeleton-dependent cytokinesis →	+0.103	+0.881	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Cytokinesis →	+0.105	+0.954	<.001	<.001	3	15
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.080	+0.923	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Mitotic cytokinesis →	+0.102	+0.937	.001	<.001	2	15
STOMACH	Golgi vesicle transport →	+0.066	+0.909	.002	<.001	3	14
STOMACH	Autophagosome organization →	+0.057	+0.758	.003	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,902 associations by consensus.

Cytoskeleton-dependent cytokinesis by THAP8 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →