THAP7-AS1

Across TCGA pan-cancer cohorts, THAP7-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated THAP7-AS1 data layer compared with 4 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher THAP7-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated THAP7-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and READ show a favorable association.

ACC, OV, and READ are the cancer types where THAP7-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.247	0.638	<.001	71	view →
OV	OS	Quartile	IV	0.688	0.276	<.001	44	view →
READ	DFS	Median	All	0.869	0.525	.002	22	view →
LGG	OS	Median	All	0.520	0.368	.001	20	view →
CHOL	OS	Tertile	All	1.000	0.595	.006	19	view →
LAML	DFS	Tertile	All	0.415	0.723	.010	14	view →
PAAD	DFS	Median	All	0.362	0.211	.018	12	view →
ESCA	OS	Tertile	All	0.793	0.581	.004	9	view →
LIHC	DFS	Tertile	All	0.463	0.652	.015	8	view →
THCA	OS	Median	II,III,IV	0.551	0.970	.026	7	view →
KIRC	DFS	Quartile	All	0.707	0.461	.021	6	view →
HNSC	DFS	Quartile	All	0.290	0.506	.008	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

THAP7-AS1–ACC (DFS)

Open the ACC breakdown →