THAP6

Across TCGA cell cohorts, THAP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,648 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible THAP6-associated GO terms across cancer lineages are Protein modification by small protein removal, DNA biosynthetic process, and Cilium or flagellum-dependent cell motility. Each is linked with THAP6 in more than 15 cancer types. Because this analysis shows association rather than direction, both THAP6-to-partner and partner-to-THAP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein modification by small protein removal grouped by THAP6-low versus THAP6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP6→partner) and Y-score (partner→THAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein modification by small protein removal →	+0.064	+0.963	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA biosynthetic process →	+0.084	+0.898	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.099	-0.630	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.099	-0.630	<.001	<.001	3	15
OVARY	Regulation of cytoplasmic mRNA processing body assembly →	+0.100	+0.750	.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.068	+0.955	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,648 associations by consensus.

Protein modification by small protein removal by THAP6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →