THAP5

Across TCGA patient cohorts, THAP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,992 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible THAP5-associated proteins across cancer lineages are PUS7, MEPCE, and TRIM24. Each is linked with THAP5 in more than 4 cancer types. Because this analysis shows association rather than direction, both THAP5-to-partner and partner-to-THAP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THAP5 versus PUS7 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP5→partner) and Y-score (partner→THAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PUS7 →	+0.324	+0.458	<.001	<.001	3	5
LSCC	MEPCE →	+0.289	+0.472	<.001	<.001	3	5
GBM	TRIM24 →	+0.438	+0.614	<.001	<.001	3	4
UCEC	ZKSCAN1 →	+0.439	+0.446	<.001	<.001	3	4
LSCC	EPS15_S221 →	-0.282	-0.454	.001	.002	3	4
LSCC	ANKRD13A →	-0.210	-0.702	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,992 associations by consensus.

THAP5 vs PUS7 — LSCC

Explore this scatter interactively →