THAP11

Across TCGA patient cohorts, THAP11 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible THAP11-associated genes across cancer lineages are SLC20A1P2, LINC02024, and SNORD114-18. Each is linked with THAP11 in more than 1 cancer types. Because this analysis shows association rather than direction, both THAP11-to-partner and partner-to-THAP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC20A1P2 grouped by THAP11-low versus THAP11-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THAP11→partner) and Y-score (partner→THAP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	SLC20A1P2 →	+0.057	+6.149	<.001	.002	3	2
LIHC	LINC02024 →	+0.057	+5.647	<.001	.004	3	2
UCEC	SNORD114-18 →	+0.484	+3.299	.001	.006	3	2
UCEC	TCP11X3P →	+0.360	+2.895	<.001	.003	3	2
LIHC	RPL12P22 →	+0.113	+6.008	<.001	.002	3	1
LIHC	SDR16C6P →	+0.050	+5.647	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

SLC20A1P2 by THAP11 expression — LIHC

Explore this box plot interactively →